Harmine, a Novel DNA Methyltransferase 1 Inhibitor in the Leukemia Cell Line
نویسندگان
چکیده
منابع مشابه
effect of harmine alkaloid on the expression of p16 and dapk in hl60 leukemia cell line
introduction: epigenetic changes such as promoter methylation of tumor suppressor genes (tsgs) is one of the most important mechanisms involved in the development of hematologic malignancies. harmine is one of the harmal-derived alkaloids with anti-proliferatory effects on leukemia cell lines. since p16 and dapk genes are hypermethylated in some hematologic malignancies, the current study aimed...
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ژورنال
عنوان ژورنال: Indian Journal of Hematology and Blood Transfusion
سال: 2017
ISSN: 0971-4502,0974-0449
DOI: 10.1007/s12288-016-0770-z